The Occurrence of Skatol in the Human Intestine
نویسنده
چکیده
The color reaction between paradimethylamidobenzaldehyde (Ehrlich’s aldehyde) and skatol’ gives us an easy method of detecting the presence and of estimating the quantity of this putrefactive product. The employment of the method in routine and experimental work upon the digestive tract has led to the accumulation of numerous observations that have an interest both for the physiologist and the physician. It is my wish to bring together here the chief results of these observations. It seems to be a general impression, at least among writers of text-books of physiological chemistry, that skatol is a regular product of intestinal putrefaction in the feces. Probably this impression is due to the statement made by Brieger to this effec%a statement which requires some modification. Among healthy children under ten years of age I have found the occurrence of skatol in the feces to be quite exceptional whether they live on a milk diet or on a mixed diet inclusive of meat. Among adults also there are many who show no trace of skatol. It is, however, true that one frequently finds a trace of skatol in the freshly voided feces of healthy individuals. Where there is an excessive degree of intestinal putrefaction there may be a marked increase in the skatol content of the feces. Whereas in persons who are normal (in the sense that they .are
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